8f2f: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8f2f is ~~ON HOLD~~

==NMR solution structure of lambda-MeuKTx-1==

~~Authors~~: ~~Harvey~~, P.J., ~~Craik~~, D.J.

== Structural highlights ==

<table><tr><td colspan='2'>[[8f2f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesobuthus_eupeus Mesobuthus eupeus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8F2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8F2F FirstGlance]. <br>

~~Description~~: ~~NMR solution structure~~ of ~~lambda~~-~~MeuKTx-1~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8f2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8f2f OCA], [https://pdbe.org/8f2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8f2f RCSB], [https://www.ebi.ac.uk/pdbsum/8f2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8f2f ProSAT]</span></td></tr>

[[Category: Craik~~, D.J~~]]

</table>

[[Category: Harvey~~, P.J~~]]

== Function ==

[https://www.uniprot.org/uniprot/CLML_MESEU CLML_MESEU] Voltage-gated potassium channel (Kv) inhibitor (Ref.2). In addition it may increase intracellular calcium release through the activation of nuclear inositol 1,4,5-trisphosphate receptors (ITPR) of cardiomyocytes, thereby causing an increase in the contraction frequency of these cells (By similarity).[UniProtKB:P0DM29][UniProtKB:P59868]

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Mesobuthus eupeus]]

[[Category: Craik DJ]]

[[Category: Harvey PJ]]

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-'''Unreleased structure'''
-The entry 8f2f is ON HOLD
+==NMR solution structure of lambda-MeuKTx-1==
+<StructureSection load='8f2f' size='340' side='right'caption='[[8f2f]]' scene=''>
-Authors: Harvey, P.J., Craik, D.J.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8f2f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesobuthus_eupeus Mesobuthus eupeus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8F2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8F2F FirstGlance]. <br>
-Description: NMR solution structure of lambda-MeuKTx-1
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8f2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8f2f OCA], [https://pdbe.org/8f2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8f2f RCSB], [https://www.ebi.ac.uk/pdbsum/8f2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8f2f ProSAT]</span></td></tr>
-[[Category: Craik, D.J]]
+</table>
-[[Category: Harvey, P.J]]
+== Function ==
+[https://www.uniprot.org/uniprot/CLML_MESEU CLML_MESEU] Voltage-gated potassium channel (Kv) inhibitor (Ref.2). In addition it may increase intracellular calcium release through the activation of nuclear inositol 1,4,5-trisphosphate receptors (ITPR) of cardiomyocytes, thereby causing an increase in the contraction frequency of these cells (By similarity).[UniProtKB:P0DM29][UniProtKB:P59868]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Mesobuthus eupeus]]
+[[Category: Craik DJ]]
+[[Category: Harvey PJ]]