1hig: Difference between revisions

Line 1:

[[Image:1hig.gif|left|200px]]<br />

[[Image:1hig.gif|left|200px]]<br /><applet load="1hig" size="350" color="white" frame="true" align="right" spinBox="true"

<applet load="1hig" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

caption="1hig, resolution 3.5Å" />

'''THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT HUMAN INTERFERON-GAMMA.'''<br />

==Overview==

The x-ray crystal structure of recombinant human interferon-gamma has been, determined with the use of multiple-isomorphous-replacement techniques., Interferon-gamma, which is dimeric in solution, crystallizes with two, dimers related by a noncrystallographic twofold axis in the asymmetric, unit. The protein is primarily alpha helical, with six helices in each, subunit that comprise approximately 62 percent of the structure; there is, no beta sheet. The dimeric structure of human interferon-gamma is, stabilized by the intertwining of helices across the subunit interface, with multiple intersubunit interactions.

The x-ray crystal structure of recombinant human interferon-gamma has been determined with the use of multiple-isomorphous-replacement techniques. Interferon-gamma, which is dimeric in solution, crystallizes with two dimers related by a noncrystallographic twofold axis in the asymmetric unit. The protein is primarily alpha helical, with six helices in each subunit that comprise approximately 62 percent of the structure; there is no beta sheet. The dimeric structure of human interferon-gamma is stabilized by the intertwining of helices across the subunit interface with multiple intersubunit interactions.

==Disease==

Line 11:

Line 10:

==About this Structure==

1HIG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1HIG OCA].

1HIG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HIG OCA].

==Reference==

Line 17:

Line 16:

[[Category: Homo sapiens]]

[[Category: Single protein]]

[[Category: Bugg, C.E.]]

[[Category: Bugg, C E.]]

[[Category: Carson, M.]]

[[Category: Cook, W.J.]]

[[Category: Cook, W J.]]

[[Category: Ealick, S.E.]]

[[Category: Ealick, S E.]]

[[Category: Nagabhushan, T.L.]]

[[Category: Nagabhushan, T L.]]

[[Category: Trotta, P.P.]]

[[Category: Trotta, P P.]]

[[Category: Vijay-Kumar, S.]]

[[Category: glycoprotein]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Mon Nov 12 17~~:18:~~28 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:01:34 2008''

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-[[Image:1hig.gif|left|200px]]<br />
+[[Image:1hig.gif|left|200px]]<br /><applet load="1hig" size="350" color="white" frame="true" align="right" spinBox="true"
-<applet load="1hig" size="450" color="white" frame="true" align="right" spinBox="true"
 caption="1hig, resolution 3.5&Aring;" />
 '''THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT HUMAN INTERFERON-GAMMA.'''<br />
 ==Overview==
-The x-ray crystal structure of recombinant human interferon-gamma has been, determined with the use of multiple-isomorphous-replacement techniques., Interferon-gamma, which is dimeric in solution, crystallizes with two, dimers related by a noncrystallographic twofold axis in the asymmetric, unit. The protein is primarily alpha helical, with six helices in each, subunit that comprise approximately 62 percent of the structure; there is, no beta sheet. The dimeric structure of human interferon-gamma is, stabilized by the intertwining of helices across the subunit interface, with multiple intersubunit interactions.
+The x-ray crystal structure of recombinant human interferon-gamma has been determined with the use of multiple-isomorphous-replacement techniques. Interferon-gamma, which is dimeric in solution, crystallizes with two dimers related by a noncrystallographic twofold axis in the asymmetric unit. The protein is primarily alpha helical, with six helices in each subunit that comprise approximately 62 percent of the structure; there is no beta sheet. The dimeric structure of human interferon-gamma is stabilized by the intertwining of helices across the subunit interface with multiple intersubunit interactions.
 ==Disease==
@@ Line 11: / Line 10: @@
 ==About this Structure==
-HIG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1HIG OCA].
+HIG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HIG OCA].
 ==Reference==
@@ Line 17: / Line 16: @@
 [[Category: Homo sapiens]]
 [[Category: Single protein]]
-[[Category: Bugg, C.E.]]
+[[Category: Bugg, C E.]]
 [[Category: Carson, M.]]
-[[Category: Cook, W.J.]]
+[[Category: Cook, W J.]]
-[[Category: Ealick, S.E.]]
+[[Category: Ealick, S E.]]
-[[Category: Nagabhushan, T.L.]]
+[[Category: Nagabhushan, T L.]]
-[[Category: Trotta, P.P.]]
+[[Category: Trotta, P P.]]
 [[Category: Vijay-Kumar, S.]]
 [[Category: glycoprotein]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 17:18:28 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:01:34 2008''