Sandbox Q123: Difference between revisions

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== Relevance ==
== Relevance ==


FN is associated with inflammation area and the process of wound healing<ref name="Proctor"/><ref name="Mosher"/>. Local treatment of fibronectin has a potential role in accelerating wound closure and the decrease in fibronectin expression can result in poorly healed wound<ref name="Ana">PMID:27554818</ref>. In addition, Fn is considered as a potential marker for radiation resistance<ref name="Fredrik">PMID:20930522</ref>.
FN is associated with inflammation area and the process of wound healing<ref name="Proctor"/><ref name="Mosher"/>. Local treatment of fibronectin has a potential role in accelerating wound closure and the decrease in fibronectin expression can result in poorly healed wound<ref name="Ana">PMID:27554818</ref>. In addition, the level of Fn expression may influence the effectiveness of cancer therapies. Based on the study of head and neck squamous cell carcinoma (HNSCC) cells by Fredrik et al., cells with high level of Fn expression show higher radioresistance compared to those with low level of Fn expression, which leads to a suggestion that Fn should be considered as a potential marker for radiation resistance<ref name="Fredrik">PMID:20930522</ref>.


== Disease ==
== Disease ==