8eyf: Difference between revisions
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==Plasmodium falciparum M1 in complex with inhibitor 15aa== | |||
<StructureSection load='8eyf' size='340' side='right'caption='[[8eyf]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8eyf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EYF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EYF FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=X4T:N-[(1R)-1-(4-bromophenyl)-2-(hydroxyamino)-2-oxoethyl]-N~2~-phenylglycinamide'>X4T</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8eyf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8eyf OCA], [https://pdbe.org/8eyf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8eyf RCSB], [https://www.ebi.ac.uk/pdbsum/8eyf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8eyf ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Calic | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Plasmodium falciparum]] | |||
[[Category: Calic PPS]] | |||
[[Category: McGowan S]] | |||
[[Category: Webb CT]] | |||