7tym: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:
'''Unreleased structure'''


The entry 7tym is ON HOLD  until Paper Publication
==Cryo-EM Structure of insulin receptor-related receptor (IRR) in active-state captured at pH 9. The 3D refinement was applied with C2 symmetry==
 
<StructureSection load='7tym' size='340' side='right'caption='[[7tym]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7tym]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TYM FirstGlance]. <br>
Description:  
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tym OCA], [https://pdbe.org/7tym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tym RCSB], [https://www.ebi.ac.uk/pdbsum/7tym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tym ProSAT]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/INSRR_HUMAN INSRR_HUMAN] Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.<ref>PMID:21641549</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bai XC]]
[[Category: Choi E]]
[[Category: Hall C]]
[[Category: Li J]]
[[Category: Wang LW]]