Sandbox Reserved 1740: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
The primary structure of cellulose sythase is a long chain of glucose units <ref> doi: 10.1016/j.pbi.2022.102273 </ref>. It is attached through Beta(1,4) linkages which appear to be like a sheet <ref> doi: 10.1016/j.pbi.2022.102273 </ref>. These features can all be seen in the rotating figure above. | The primary structure of cellulose sythase is a long chain of glucose units <ref> doi: 10.1016/j.pbi.2022.102273 </ref>. It is attached through Beta(1,4) linkages which appear to be like a sheet making up the structures secondary structure of the protein. <ref> doi: 10.1016/j.pbi.2022.102273 </ref>. These features can all be seen in the rotating figure above. | ||
Beta linkages form <scene name='91/919049/Beta_sheets/2'>Beta sheets</scene>, 6 stranded beta sheets to be exact along with the beta sheets there can be found the 5 <scene name='91/919049/Helix/1'>alpha helices</scene>. These chains form hydrogen bonds with each other forming microfibrils helping to create the overall strength and stability of cellulose <ref> doi: 10.1093/femsre/fuab051 </ref>. Though much research has been done, the tertiary structure of cellulose synthase has been difficult to find because of complications with things like purification of the active enzyme, and the overall difficulty of crystalizing plant cellulose synthase. In the 3D model that we have displayed is that of a bacterial cellulose synthase. | Beta linkages form <scene name='91/919049/Beta_sheets/2'>Beta sheets</scene>, 6 stranded beta sheets to be exact along with the beta sheets there can be found the 5 <scene name='91/919049/Helix/1'>alpha helices</scene>. These chains form hydrogen bonds with each other forming microfibrils helping to create the overall strength and stability of cellulose <ref> doi: 10.1093/femsre/fuab051 </ref>. Though much research has been done, the tertiary and quinary structure of cellulose synthase has been difficult to find because of complications with things like purification of the active enzyme, and the overall difficulty of crystalizing plant cellulose synthase. In the 3D model that we have displayed is that of a bacterial cellulose synthase. With the use of of technology and what we know about bacterial cellulose synthase there have been projected images of the tertiary and quaternary structure. The bacterial cellulose synthase is similar to a plants cellulose synthase in that the cell membrane, using <scene name='91/919049/Cellulose_and_udp/2'>UDP (orange)</scene>-glucose from the cytoplasm, passing through the cell membrane, and extruding <scene name='91/919049/Cellulose_and_udp/2'>cellulose (purple)</scene> outside the cell. | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
