8by5: Difference between revisions
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==C. elegans TOFU-6 eTUDOR TOFU-1 peptide complex== | |||
<StructureSection load='8by5' size='340' side='right'caption='[[8by5]], [[Resolution|resolution]] 1.73Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8by5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BY5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BY5 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
[[Category: Falk | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8by5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8by5 OCA], [https://pdbe.org/8by5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8by5 RCSB], [https://www.ebi.ac.uk/pdbsum/8by5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8by5 ProSAT]</span></td></tr> | ||
[[Category: Ketting | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/TOFU6_CAEEL TOFU6_CAEEL] Component of the pid-1 and tost-1 variants of the PETISCO complexes, which have roles in the biogenesis of a class of 21 nucleotide PIWI-interacting RNAs (piRNAs) that possess a uracil residue at the 5'-end (also called 21U-RNAs) and embryogenesis, respectively (PubMed:31147388, PubMed:31216475). Promotes the biogenesis of 21U-RNAs (PubMed:31216475). Required for chromosome segregation and cell division in early embryos (PubMed:17171368, PubMed:31216475). May have a role in DNA replication (PubMed:17171368).<ref>PMID:17171368</ref> <ref>PMID:31147388</ref> <ref>PMID:31216475</ref> <ref>PMID:31216475</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Caenorhabditis elegans]] | |||
[[Category: Large Structures]] | |||
[[Category: Falk S]] | |||
[[Category: Ketting R]] | |||