8hu6: Difference between revisions

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'''Unreleased structure'''


The entry 8hu6 is ON HOLD
==AMP deaminase 2 in complex with AMP==
 
<StructureSection load='8hu6' size='340' side='right'caption='[[8hu6]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8hu6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HU6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HU6 FirstGlance]. <br>
Description:  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hu6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hu6 OCA], [https://pdbe.org/8hu6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hu6 RCSB], [https://www.ebi.ac.uk/pdbsum/8hu6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hu6 ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/AMPD2_HUMAN AMPD2_HUMAN] Autosomal recessive spastic paraplegia type 63;Pontocerebellar hypoplasia type 9. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/AMPD2_HUMAN AMPD2_HUMAN] AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle.<ref>PMID:23911318</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Adachi T]]
[[Category: Doi S]]