Sandbox Q123: Difference between revisions
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== Structural insights == | == Structural insights == | ||
<scene name='93/932569/Fn/6'>Fibronectin (FN)</scene> is a dimer of homologous monomers linked by S-S bond. Each monomer contains 3 types of repeating units: <scene name='93/932569/Fn_i/2'>FN I</scene>, <scene name='93/932569/Fn_ii/3'>FN II</scene> and <scene name='93/932569/Fn_iii/3'>FN III</scene>. Type I and type II repeats are disulfide-bonded loops, containing about 45 and 60 amino-acids each, while type III repeats are about 90 amino-acids long without S-S bonds<ref name="Pancov">PMID:12244123</ref><ref name="Proctor">PMID:3326130</ref><ref name="Richard">PMID:3916323</ref>. Each module contains several numbered protein binding domains, i.e., | <scene name='93/932569/Fn/6'>Fibronectin (FN)</scene> is a dimer of homologous monomers linked by S-S bond. Each monomer contains 3 types of repeating units: <scene name='93/932569/Fn_i/2'>FN I</scene>, <scene name='93/932569/Fn_ii/3'>FN II</scene> and <scene name='93/932569/Fn_iii/3'>FN III</scene>. Type I and type II repeats are disulfide-bonded loops, containing about 45 and 60 amino-acids each, while type III repeats are about 90 amino-acids long without S-S bonds<ref name="Pancov">PMID:12244123</ref><ref name="Proctor">PMID:3326130</ref><ref name="Richard">PMID:3916323</ref>. Each module contains several numbered protein binding domains, i.e., repeat No.6, No.7-9 of FN I and repeat No.1-2 of FN II are the gelatin binding domain (GBD). | ||
== Biological Functions == | == Biological Functions == | ||