8fsz: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8fsz is ~~ON HOLD until Paper Publication~~

==Full-length mouse 5-HT3A receptor in complex with ALB148471, open-like==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8fsz]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FSZ OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=8FSZ FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.79Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=Y7H:5-[(1R,3S,5R)-1-azabicyclo[3.2.2]nonan-3-yl]-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indazol-6-one'>Y7H</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=8fsz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fsz OCA], [https://pdbe.org/8fsz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fsz RCSB], [https://www.ebi.ac.uk/pdbsum/8fsz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fsz ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/5HT3A_MOUSE 5HT3A_MOUSE] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Mus musculus]]

[[Category: Chakrapani S]]

[[Category: Felt KC]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8fsz is ON HOLD  until Paper Publication
+==Full-length mouse 5-HT3A receptor in complex with ALB148471, open-like==
+<StructureSection load='8fsz' size='340' side='right'caption='[[8fsz]], [[Resolution|resolution]] 3.79&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8fsz]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FSZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FSZ FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.79&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=Y7H:5-[(1R,3S,5R)-1-azabicyclo[3.2.2]nonan-3-yl]-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indazol-6-one'>Y7H</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fsz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fsz OCA], [https://pdbe.org/8fsz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fsz RCSB], [https://www.ebi.ac.uk/pdbsum/8fsz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fsz ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/5HT3A_MOUSE 5HT3A_MOUSE] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Mus musculus]]
+[[Category: Chakrapani S]]
+[[Category: Felt KC]]