7fso: Difference between revisions
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The | ==SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z198195770== | ||
<StructureSection load='7fso' size='340' side='right'caption='[[7fso]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7fso]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FSO FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=LJA:N-[3-(carbamoylamino)phenyl]acetamide'>LJA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fso OCA], [https://pdbe.org/7fso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fso RCSB], [https://www.ebi.ac.uk/pdbsum/7fso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fso ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/SDCB1_HUMAN SDCB1_HUMAN] Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.<ref>PMID:10230395</ref> <ref>PMID:11179419</ref> <ref>PMID:11498591</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Bountra C]] | |||
[[Category: Bradshaw WJ]] | |||
[[Category: Brennan PE]] | |||
[[Category: Katis VL]] | |||
[[Category: Von Delft F]] | |||
Revision as of 10:18, 15 February 2023
SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z198195770
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