8g2m: Difference between revisions
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==The tumor activated anti-CTLA-4 monoclonal antibody XTX101 demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer== | |||
<StructureSection load='8g2m' size='340' side='right'caption='[[8g2m]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8g2m]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Peptide_display_vector_fth1 Peptide display vector fth1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8G2M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8G2M FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr> | ||
[[Category: Williams | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8g2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8g2m OCA], [https://pdbe.org/8g2m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8g2m RCSB], [https://www.ebi.ac.uk/pdbsum/8g2m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8g2m ProSAT]</span></td></tr> | ||
</table> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Peptide display vector fth1]] | |||
[[Category: Williams JC]] | |||
Revision as of 07:19, 14 February 2024
The tumor activated anti-CTLA-4 monoclonal antibody XTX101 demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer
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