8ia2: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
m Protected "8ia2" [edit=sysop:move=sysop]
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
Line 1: Line 1:
'''Unreleased structure'''


The entry 8ia2 is ON HOLD  until Paper Publication
==Structure of C5a bound human C5aR1 in complex with Go (Composite map)==
 
<StructureSection load='8ia2' size='340' side='right'caption='[[8ia2]], [[Resolution|resolution]] 3.21&Aring;' scene=''>
Authors: Yadav, M.K., Yadav, R., Maharana, J., Banerjee, R., Shukla, A.K., Gati, C.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8ia2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IA2 FirstGlance]. <br>
Description: Structure of C5a bound human C5aR1 in complex with Go (Composite map)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.21&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ia2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ia2 OCA], [https://pdbe.org/8ia2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ia2 RCSB], [https://www.ebi.ac.uk/pdbsum/8ia2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ia2 ProSAT]</span></td></tr>
[[Category: Shukla, A.K]]
</table>
[[Category: Yadav, R]]
== Function ==
[[Category: Yadav, M.K]]
[https://www.uniprot.org/uniprot/C5AR1_HUMAN C5AR1_HUMAN] Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).<ref>PMID:10636859</ref> <ref>PMID:15153520</ref> <ref>PMID:1847994</ref> <ref>PMID:7622471</ref> <ref>PMID:8182049</ref> <ref>PMID:9553099</ref>
[[Category: Maharana, J]]
== References ==
[[Category: Banerjee, R]]
<references/>
[[Category: Gati, C]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Banerjee R]]
[[Category: Gati C]]
[[Category: Maharana J]]
[[Category: Shukla AK]]
[[Category: Yadav MK]]
[[Category: Yadav R]]
Retrieved from "https://proteopedia.org/8ia2"