8gan: Difference between revisions
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==Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications== | |||
<StructureSection load='8gan' size='340' side='right'caption='[[8gan]], [[Resolution|resolution]] 3.26Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8gan]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_lactamica Neisseria lactamica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GAN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GAN FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.26Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gan OCA], [https://pdbe.org/8gan PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gan RCSB], [https://www.ebi.ac.uk/pdbsum/8gan PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gan ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/D0W8X4_NEILA D0W8X4_NEILA] CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).[PIRNR:PIRNR029950] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Neisseria lactamica]] | |||
[[Category: Hu C]] | |||
[[Category: Ke A]] | |||
[[Category: Nam KH]] | |||
Latest revision as of 12:03, 6 March 2024
Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications
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