8i7e: Difference between revisions
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==Crystal structure of Glyceraldehyde 3-phosphate dehydrogenase from Salmonella typhi at 2.05A== | |||
<StructureSection load='8i7e' size='340' side='right'caption='[[8i7e]], [[Resolution|resolution]] 2.05Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8i7e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhi Salmonella enterica subsp. enterica serovar Typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8I7E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8I7E FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8i7e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8i7e OCA], [https://pdbe.org/8i7e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8i7e RCSB], [https://www.ebi.ac.uk/pdbsum/8i7e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8i7e ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/A0A4S3IK62_SALET A0A4S3IK62_SALET] Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.[ARBA:ARBA00003501] | ||
[[Category: | __TOC__ | ||
[[Category: Kumar | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Salmonella enterica subsp. enterica serovar Typhi]] | ||
[[Category: | [[Category: Chaubey GK]] | ||
[[Category: | [[Category: Chaudhary S]] | ||
[[Category: Raje | [[Category: Dhiman A]] | ||
[[Category: | [[Category: Dilawari R]] | ||
[[Category: | [[Category: Kumar A]] | ||
[[Category: Kumar N]] | |||
[[Category: Kumaran S]] | |||
[[Category: Modanwal R]] | |||
[[Category: Patidar A]] | |||
[[Category: Raje CI]] | |||
[[Category: Raje M]] | |||
[[Category: Talukdar S]] | |||
Latest revision as of 06:24, 6 September 2023
Crystal structure of Glyceraldehyde 3-phosphate dehydrogenase from Salmonella typhi at 2.05A
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