1k2k: Difference between revisions

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[[Image:1k2k.~~gif~~|left|200px]]

[[Image:1k2k.png|left|200px]]

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~~'''~~NMR MINIMIZED AVERAGE STRUCTURE OF d(CGTACG)2~~'''~~

===NMR MINIMIZED AVERAGE STRUCTURE OF d(CGTACG)2===

~~==Overview==~~

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~~Solution structures and base pair stacking of a self- complementary DNA hexamer d(CGTACG)(2) have been studied at 5~~, ~~10 and 15 degrees C~~, ~~respectively. The stacking interactions among~~ the ~~center base pair steps of the DNA duplex are found~~ to ~~improve when~~ the ~~terminal base pairs became less stable due to end fraying~~. ~~A new structural quantity, the stacking sum (Sigma(s)~~), is ~~introduced to indicate small changes in~~ the stacking overlaps between base pairs. The improvements in the stacking overlaps to maintain the double helical conformation are probably the cause for the observed temperature dependent structural changes in double helical DNA molecule. A detailed analysis of the helical parameters, backbone torsion angles, base orientations and sugar conformations of these structures has been performed.

The line below this paragraph, {{ABSTRACT_PUBMED_11922844}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 11922844 is the PubMed ID number.

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==About this Structure==

Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K2K OCA].

Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K2K OCA].

==Reference==

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[[Category: Lam, S L.]]

[[Category: Self-complementary dna]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri May~~ ~~2 22~~:13:27 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 21:32:48 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1k2k.gif|left|200px]]
+{{Seed}}
+[[Image:1k2k.png|left|200px]]
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@@ Line 9: / Line 10: @@
 {{STRUCTURE_1k2k|  PDB=1k2k  |  SCENE=  }}
-'''NMR MINIMIZED AVERAGE STRUCTURE OF d(CGTACG)2'''
+===NMR MINIMIZED AVERAGE STRUCTURE OF d(CGTACG)2===
-==Overview==
+<!--
-Solution structures and base pair stacking of a self- complementary DNA hexamer d(CGTACG)(2) have been studied at 5, 10 and 15 degrees C, respectively. The stacking interactions among the center base pair steps of the DNA duplex are found to improve when the terminal base pairs became less stable due to end fraying. A new structural quantity, the stacking sum (Sigma(s)), is introduced to indicate small changes in the stacking overlaps between base pairs. The improvements in the stacking overlaps to maintain the double helical conformation are probably the cause for the observed temperature dependent structural changes in double helical DNA molecule. A detailed analysis of the helical parameters, backbone torsion angles, base orientations and sugar conformations of these structures has been performed.
+The line below this paragraph, {{ABSTRACT_PUBMED_11922844}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 11922844 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_11922844}}
 ==About this Structure==
-Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K2K OCA].
+Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K2K OCA].
 ==Reference==
@@ Line 23: / Line 27: @@
 [[Category: Lam, S L.]]
 [[Category: Self-complementary dna]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 22:13:27 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 21:32:48 2008''