8fx5: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Human M4 muscarinic acetylcholine receptor complex with Gi1 and xanomeline== | |||
<StructureSection load='8fx5' size='340' side='right'caption='[[8fx5]], [[Resolution|resolution]] 2.45Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8fx5]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FX5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FX5 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.45Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XNO:xanomeline'>XNO</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fx5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fx5 OCA], [https://pdbe.org/8fx5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fx5 RCSB], [https://www.ebi.ac.uk/pdbsum/8fx5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fx5 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ACM4_HUMAN ACM4_HUMAN] The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase. | |||
==See Also== | |||
*[[Transducin 3D structures|Transducin 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Sexton | [[Category: Danev R]] | ||
[[Category: | [[Category: Glukhova A]] | ||
[[Category: | [[Category: Mobbs JI]] | ||
[[Category: Sexton PM]] | |||
[[Category: Thal DM]] | |||
[[Category: Vuckovic Z]] | |||
Revision as of 11:15, 14 March 2024
Human M4 muscarinic acetylcholine receptor complex with Gi1 and xanomeline
| ||||||||||||
