1k6f: Difference between revisions

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[[Image:1k6f.~~jpg~~|left|200px]]

[[Image:1k6f.png|left|200px]]

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~~'''~~Crystal Structure of the Collagen Triple Helix Model [(Pro-Pro-Gly)10]3~~'''~~

===Crystal Structure of the Collagen Triple Helix Model [(Pro-Pro-Gly)10]3===

~~==Overview==~~

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~~The first report of the full-length structure of the collagen-like polypeptide [(Pro~~-~~Pro~~-~~Gly)(10)](3) is given. This structure was obtained from crystals grown in a microgravity environment, which diffracted up to 1.3 A, using synchrotron radiation.~~ The ~~final model~~, ~~which was refined to an R(factor) of 0.18~~, is the ~~highest-resolution description of a collagen triple helix reported~~ to ~~date. This structure provides clues regarding a series of aspects related to collagen triple helix structure and assembly. The strict dependence of proline puckering~~ on ~~the position inside the Pro-Pro-Gly triplets and the correlation between backbone and side chain dihedral angles support the propensity-based mechanism of triple helix stabilization~~/~~destabilization induced by hydroxyproline~~. ~~Furthermore, the analysis of [(Pro-Pro-Gly)(10)](3~~) ~~packing~~, ~~which~~ is ~~governed by electrostatic interactions, suggests that charges may act as locking features in the axial organization of triple helices in~~ the ~~collagen fibrils~~.

The line below this paragraph, {{ABSTRACT_PUBMED_11790836}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 11790836 is the PubMed ID number.

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==About this Structure==

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[[Category: Puckering]]

[[Category: Triple helix]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri May~~ 2 22:21:44 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 09:51:15 2008''

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-[[Image:1k6f.jpg|left|200px]]
+{{Seed}}
+[[Image:1k6f.png|left|200px]]
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 {{STRUCTURE_1k6f|  PDB=1k6f  |  SCENE=  }}
-'''Crystal Structure of the Collagen Triple Helix Model [(Pro-Pro-Gly)10]3'''
+===Crystal Structure of the Collagen Triple Helix Model [(Pro-Pro-Gly)10]3===
-==Overview==
+<!--
-The first report of the full-length structure of the collagen-like polypeptide [(Pro-Pro-Gly)(10)](3) is given. This structure was obtained from crystals grown in a microgravity environment, which diffracted up to 1.3 A, using synchrotron radiation. The final model, which was refined to an R(factor) of 0.18, is the highest-resolution description of a collagen triple helix reported to date. This structure provides clues regarding a series of aspects related to collagen triple helix structure and assembly. The strict dependence of proline puckering on the position inside the Pro-Pro-Gly triplets and the correlation between backbone and side chain dihedral angles support the propensity-based mechanism of triple helix stabilization/destabilization induced by hydroxyproline. Furthermore, the analysis of [(Pro-Pro-Gly)(10)](3) packing, which is governed by electrostatic interactions, suggests that charges may act as locking features in the axial organization of triple helices in the collagen fibrils.
+The line below this paragraph, {{ABSTRACT_PUBMED_11790836}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 11790836 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_11790836}}
 ==About this Structure==
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 [[Category: Puckering]]
 [[Category: Triple helix]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 22:21:44 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 09:51:15 2008''