Sandbox Reserved 1790: Difference between revisions
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{{BAMBED | {{BAMBED | ||
|DATE= | |DATE=March 17, 2023 | ||
|OLDID=2607465 | |OLDID=2607465 | ||
|BAMBEDDOI=10.1002/bmb.21026 | |BAMBEDDOI=10.1002/bmb.21026 | ||
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== Introduction == | == Introduction == | ||
''' | '''SHOC2-PP1C-MRAS''' is a ternary complex formed by the individual proteins: SHOC2, PP1C, and MRAS. Formation of this complex begins with a signal binding to a receptor tyrosine kinase receptor(RTK). This causes membrane bound MRAS to exchange GDP for GTP. From here the complex comes together and is able to dephosphorylate the RAF complex leading to further downstream signaling effects. | ||
[[Image:LPA_in_membrane4.fw.png|200px|center|thumb|'''Figure 1:''' LPA receptor (blue) bound to the cell membrane. The binding pocket is highlighted in red. The added bRIL protein is highlighted in orange.]] | [[Image:LPA_in_membrane4.fw.png|200px|center|thumb|'''Figure 1:''' LPA receptor (blue) bound to the cell membrane. The binding pocket is highlighted in red. The added bRIL protein is highlighted in orange.]] | ||
