Sandbox Reserved 1769: Difference between revisions
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=== Mechanism of Bile Salt Uptake === | === Mechanism of Bile Salt Uptake === | ||
Bile salts recognize and bind to the <scene name='95/952697/Ntcp_open-pore_state_surface/1'> | Bile salts recognize and bind to the <scene name='95/952697/Ntcp_open-pore_state_surface/1'>open-pore state</scene>. After binding, bile salts pass through the amphipathic pore and NTCP transitions into the <scene name='95/952697/Ntcp_inward_facing_state/1'>inward facing state</scene>. In this conformation, the pore once open to the extracellular side is now closed and is now open to the cytoplasmic side. Transition to the inward facing state allows release of bile salts and sodium ions. It is not yet known how this transition exactly proceeds. | ||
=== Mechanism of HBV/HDV Infection === | === Mechanism of HBV/HDV Infection === | ||