Sandbox Reserved 1788: Difference between revisions
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|BAMBEDDOI=10.1002/bmb.21026 | |BAMBEDDOI=10.1002/bmb.21026 | ||
}} | }} | ||
==SHOC2-PP1C-MRAS== | ==SHOC2-PP1C-MRAS== | ||
<StructureSection load='7UPI' size='340' side='right' caption='SHOC2-MRAS-PP1C'> | <StructureSection load='7UPI' size='340' side='right' caption='SHOC2-MRAS-PP1C'> | ||
== Introduction == | == Introduction == | ||
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[[Image:LPA_in_membrane4.fw.png|200px|center|thumb|'''Figure 1:''' LPA receptor (blue) bound to the cell membrane. The binding pocket is highlighted in red. The added bRIL protein is highlighted in orange.]] | [[Image:LPA_in_membrane4.fw.png|200px|center|thumb|'''Figure 1:''' LPA receptor (blue) bound to the cell membrane. The binding pocket is highlighted in red. The added bRIL protein is highlighted in orange.]] | ||
== Overall Structure == | == Overall Structure == | ||
=== SHOC2 === | === SHOC2 === | ||
<scene name='95/952717/Shoc2/1'>SHOC2</scene> | |||
=== PP1C === | === PP1C === | ||
<scene name='95/952717/Pp1c/1'>PP1C</scene> | |||
=== MRAS === | === MRAS === | ||
<scene name='95/ | <scene name='95/952717/Mras/2'>MRAS</scene> | ||
=== Key Ligand Interactions === | === Key Ligand Interactions === | ||
[[Image:Amphbindingfinal.png|275 px|right|thumb|'''Figure 3''': Electrostatic illustration of the amphipathic binding pocket of the LPA<sub>1</sub> receptor. This binding pocket was revealed by cutting away the exterior or the protein. This binding pocket, located in the interior of the protein, has both polar and nonpolar regions. The blue and red coloration highlight the positively and negatively charged regions, respectively, and the white color shows the nonpolar region of the binding pocket.]] | [[Image:Amphbindingfinal.png|275 px|right|thumb|'''Figure 3''': Electrostatic illustration of the amphipathic binding pocket of the LPA<sub>1</sub> receptor. This binding pocket was revealed by cutting away the exterior or the protein. This binding pocket, located in the interior of the protein, has both polar and nonpolar regions. The blue and red coloration highlight the positively and negatively charged regions, respectively, and the white color shows the nonpolar region of the binding pocket.]] | ||
=== SHOC2 and PP1C === | === SHOC2 and PP1C === | ||
=== SHOC2 and MRAS === | === SHOC2 and MRAS === | ||
=== PP1C and MRAS === | === PP1C and MRAS === | ||
