Sandbox Reserved 1769: Difference between revisions
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== Medical Relevance == | == Medical Relevance == | ||
Bile salts are derived from [https://en.wikipedia.org/wiki/Cholesterol cholesterol], and they serve an important role in the mechanical digestion of fats and ultimately facilitate the chemical digestion of lipids. The amphipathicity (INSERT BLUE LINK) allows them to do this, solubilizing hydrophobic fats for transport in aqueous bodily fluids. Without bile salts, fats would spontaneously separate out of the aqueous solution in the duodenum and would not be accessible [https://en.wikipedia.org/wiki/Pancreatic_lipase_family#Human_pancreatic_lipase pancreatic lipase] for breakdown. Proper fat digestion requires both pancreatic lipase and bile; thus, NTCP's function in recycling bile salts is critical. | |||
</StructureSection> | </StructureSection> | ||
