Sandbox Reserved 1780: Difference between revisions
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===TSH Agonist=== | ===TSH Agonist=== | ||
Thyroid-stimulating hormone (TSH) (GREEN LINK) is a hormone that stimulates the thyroid gland to produce proteins that are vital for many metabolic pathways in the body's tissue. TSH activates the TSHR protein by binding to the concave surface of the LRRD and hinge region to keep TSHR in its active state by clashing with the membrane <ref name="Duan"> DOI:10.1038/s41586-022-05173-3</ref>. (Figure 2). This clash is caused by glycosylations of an asparagine 52 residue on the alpha subunit of TSH (GREEN LINK). These modifications to the ASN residue are N-acetyl glucosamine modifications (Figure 3). | Thyroid-stimulating hormone (TSH) (GREEN LINK) is a hormone that stimulates the thyroid gland to produce proteins that are vital for many metabolic pathways in the body's tissue. TSH activates the TSHR protein by binding to the concave surface of the LRRD and hinge region to keep TSHR in its active state by clashing with the membrane <ref name="Duan"> DOI:10.1038/s41586-022-05173-3</ref>. [[Image:NAG.png|200 px|left|thumb|Figure 3]] (Figure 2). This clash is caused by glycosylations of an asparagine 52 residue on the alpha subunit of TSH (GREEN LINK). These modifications to the ASN residue are N-acetyl glucosamine modifications (Figure 3). | ||
