Sandbox Reserved 1769: Difference between revisions
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=== Domains === | === Domains === | ||
NTCP contains <scene name='95/952697/Ntcp_open-pore_state/21'>two characteristic domains</scene>: the core and panel domains (Figure 3). Movement of these two domains allows recognition and transport of bile acids into hepatocytes. | NTCP contains <scene name='95/952697/Ntcp_open-pore_state/21'>two characteristic domains</scene>: the core and panel domains (Figure 3). Movement of these two domains allows recognition and transport of bile acids into hepatocytes. | ||
*<b><font color="orange">Panel Domain</font></b>: <scene name='95/952697/Ntcp_open-pore_state/23'> | *<b><font color="orange">Panel Domain</font></b>: <scene name='95/952697/Ntcp_open-pore_state/23'>TM helices 1, 5, 6</scene> | ||
** Formed by transmembrane helices TM1, TM5, and TM6. | ** Formed by transmembrane helices TM1, TM5, and TM6. | ||
*<b><font color="#0040e0">Core domain</font></b>: <scene name='95/952697/Ntcp_open-pore_state/24'>Residues 45-154, 209-309</scene> | *<b><font color="#0040e0">Core domain</font></b>: <scene name='95/952697/Ntcp_open-pore_state/24'>Residues 45-154, 209-309</scene> | ||