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'''Unreleased structure'''


The entry 8ok0 is ON HOLD
==Crystal structure of human NQO1 in complex with the inhibitor PMSF==
 
<StructureSection load='8ok0' size='340' side='right'caption='[[8ok0]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
Authors: Martin-Garcia, J.M., Grieco, A., Ruiz-Fresneda, M.A.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8ok0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OK0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OK0 FirstGlance]. <br>
Description: Crystal structure of human NQO1 in complex with the inhibitor PMSF
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PMS:PHENYLMETHANESULFONIC+ACID'>PMS</scene></td></tr>
[[Category: Grieco, A]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ok0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ok0 OCA], [https://pdbe.org/8ok0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ok0 RCSB], [https://www.ebi.ac.uk/pdbsum/8ok0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ok0 ProSAT]</span></td></tr>
[[Category: Ruiz-Fresneda, M.A]]
</table>
[[Category: Martin-Garcia, J.M]]
== Function ==
[https://www.uniprot.org/uniprot/NQO1_HUMAN NQO1_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Grieco A]]
[[Category: Martin-Garcia JM]]
[[Category: Ruiz-Fresneda MA]]
Retrieved from "https://proteopedia.org/8ok0"