1jkw: Difference between revisions

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[[Image:1jkw.gif|left|200px]]<br />

[[Image:1jkw.gif|left|200px]]<br /><applet load="1jkw" size="350" color="white" frame="true" align="right" spinBox="true"

<applet load="1jkw" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

caption="1jkw, resolution 2.6Å" />

'''STRUCTURE OF CYCLIN MCS2'''<br />

==Overview==

The crystal structure of human cyclin H has been solved at 2.6 A, resolution by the MIR method and refined to an R-factor of 23.1%. The core, of the molecule consists of two helical repeats adopting the canonical, cyclin fold already observed in the structures of cyclin A [Brown et al., (1995) Structure 3, 1235-1247; Jeffrey et al. (1995) Nature 376, 313-320;, Russo et al. (1996) Nature 382, 325-331] and TFIIB [Nikoilov et al. (1995), Nature 377, 119-128]. The N-terminal and C-terminal residues form a new, domain built on two long helices interacting essentially with the first, repeat of the molecule.

The crystal structure of human cyclin H has been solved at 2.6 A resolution by the MIR method and refined to an R-factor of 23.1%. The core of the molecule consists of two helical repeats adopting the canonical cyclin fold already observed in the structures of cyclin A [Brown et al. (1995) Structure 3, 1235-1247; Jeffrey et al. (1995) Nature 376, 313-320; Russo et al. (1996) Nature 382, 325-331] and TFIIB [Nikoilov et al. (1995) Nature 377, 119-128]. The N-terminal and C-terminal residues form a new domain built on two long helices interacting essentially with the first repeat of the molecule.

==About this Structure==

1JKW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1JKW OCA].

1JKW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKW OCA].

==Reference==

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[[Category: Moras, D.]]

[[Category: Poterszman, A.]]

[[Category: Thierry, J.C.]]

[[Category: Thierry, J C.]]

[[Category: cell cycle]]

[[Category: cell division]]

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[[Category: nuclear protein]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Mon Nov 12 17~~:41:~~56 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:23:46 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1jkw.gif|left|200px]]<br />
+[[Image:1jkw.gif|left|200px]]<br /><applet load="1jkw" size="350" color="white" frame="true" align="right" spinBox="true"
-<applet load="1jkw" size="450" color="white" frame="true" align="right" spinBox="true"
 caption="1jkw, resolution 2.6&Aring;" />
 '''STRUCTURE OF CYCLIN MCS2'''<br />
 ==Overview==
-The crystal structure of human cyclin H has been solved at 2.6 A, resolution by the MIR method and refined to an R-factor of 23.1%. The core, of the molecule consists of two helical repeats adopting the canonical, cyclin fold already observed in the structures of cyclin A [Brown et al., (1995) Structure 3, 1235-1247; Jeffrey et al. (1995) Nature 376, 313-320;, Russo et al. (1996) Nature 382, 325-331] and TFIIB [Nikoilov et al. (1995), Nature 377, 119-128]. The N-terminal and C-terminal residues form a new, domain built on two long helices interacting essentially with the first, repeat of the molecule.
+The crystal structure of human cyclin H has been solved at 2.6 A resolution by the MIR method and refined to an R-factor of 23.1%. The core of the molecule consists of two helical repeats adopting the canonical cyclin fold already observed in the structures of cyclin A [Brown et al. (1995) Structure 3, 1235-1247; Jeffrey et al. (1995) Nature 376, 313-320; Russo et al. (1996) Nature 382, 325-331] and TFIIB [Nikoilov et al. (1995) Nature 377, 119-128]. The N-terminal and C-terminal residues form a new domain built on two long helices interacting essentially with the first repeat of the molecule.
 ==About this Structure==
-JKW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1JKW OCA].
+JKW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKW OCA].
 ==Reference==
@@ Line 17: / Line 16: @@
 [[Category: Moras, D.]]
 [[Category: Poterszman, A.]]
-[[Category: Thierry, J.C.]]
+[[Category: Thierry, J C.]]
 [[Category: cell cycle]]
 [[Category: cell division]]
@@ Line 23: / Line 22: @@
 [[Category: nuclear protein]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 17:41:56 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:23:46 2008''