8ivd: Difference between revisions
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The entry | ==COMPLEX STRUCTURE OF CD93-IGFBP7== | ||
<StructureSection load='8ivd' size='340' side='right'caption='[[8ivd]], [[Resolution|resolution]] 3.24Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8ivd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IVD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IVD FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.24Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ivd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ivd OCA], [https://pdbe.org/8ivd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ivd RCSB], [https://www.ebi.ac.uk/pdbsum/8ivd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ivd ProSAT]</span></td></tr> | ||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/IBP7_HUMAN IBP7_HUMAN] Familial retinal arterial macroaneurysm. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/IBP7_HUMAN IBP7_HUMAN] Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.<ref>PMID:8117260</ref> <ref>PMID:8939990</ref> [https://www.uniprot.org/uniprot/C1QR1_HUMAN C1QR1_HUMAN] Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion. | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Song GJ]] | |||
[[Category: Xu YM]] | |||
