Sandbox Reserved 1777: Difference between revisions
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NTpS can bind to the PP1C active site without PP1C also being bound to SHOC2 and MRAS, however the catalytic activity is much slower and the reaction is less efficient. Also for this event to occur NTpS would need to be exposed from its binding site in the inactive RAF complex. A RAS has to bind to RAF to expose the NTpS allowing PP1C and NTpS to bind. | NTpS can bind to the PP1C active site without PP1C also being bound to SHOC2 and MRAS, however the catalytic activity is much slower and the reaction is less efficient. Also for this event to occur NTpS would need to be exposed from its binding site in the inactive RAF complex. A RAS has to bind to RAF to expose the NTpS allowing PP1C and NTpS to bind. | ||
<scene name='95/952705/Pp1c_active_site/5'>TextToBeDisplayed</scene> '''let me know thought on the style of image''' | |||
=Activation of RAF= | =Activation of RAF= | ||
[[Image:Screen Shot 2023-04-10 at 4.34.56 PM.jpeg|600px|thumb|<font size="2"><div style="text-align: center;">'''Figure 3'''. Schematic representation of RAF activation. </div></font>]] | [[Image:Screen Shot 2023-04-10 at 4.34.56 PM.jpeg|600px|thumb|<font size="2"><div style="text-align: center;">'''Figure 3'''. Schematic representation of RAF activation. </div></font>]] | ||
