Sandbox Reserved 1791: Difference between revisions

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== Biological Relevance ==

[[Image:T3t4levels.jpeg|~~300~~ px|right|thumb|Figure 4: T3 and T4 role in TSH concentration: Highlighting the problem when under or overactive on the metabolism. When an antibody is bound to TSHR and cannot respond to the negative feedback look the metabolism experiences a shift outside of equilibrium resulting in a wide array of side effects. [https://commons.wikimedia.org/wiki/File:1813_A_Classic_Negative_Feedback_Loop.jpg]]]

[[Image:T3t4levels.jpeg|400 px|right|thumb|Figure 4: T3 and T4 role in TSH concentration: Highlighting the problem when under or overactive on the metabolism. When an antibody is bound to TSHR and cannot respond to the negative feedback look the metabolism experiences a shift outside of equilibrium resulting in a wide array of side effects. [https://commons.wikimedia.org/wiki/File:1813_A_Classic_Negative_Feedback_Loop.jpg]]]

The thyroid plays an essential role in the body's metabolism. The body's metabolism affects things like heart rate, digestion, temperature regulation, and many more things. When TSH is bound to TSHR, a signal is sent to produce T3 and T4. T4 is considered an inactive form and needs to be converted into T3 to become active. Those hormones then go impact cells in your body to increase or decrease your metabolism. The T3 and T4 hormones use a feedback system to regulate the release of TSH. When the hormone levels are high they travel through the bloodstream to prevent TSH production. When the hormones are low they are not able to continue the negative feedback loop, thus allowing TSH to be released to bind to TSHR.

=== Hyperthyroidism ===

Sandbox Reserved 1791: Difference between revisions

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 == Biological Relevance ==
-[[Image:T3t4levels.jpeg|300 px|right|thumb|Figure 4: T3 and T4 role in TSH concentration: Highlighting the problem when under or overactive on the metabolism. When an antibody is bound to TSHR and cannot respond to the negative feedback look the metabolism experiences a shift outside of equilibrium resulting in a wide array of side effects. [https://commons.wikimedia.org/wiki/File:1813_A_Classic_Negative_Feedback_Loop.jpg]]]
+[[Image:T3t4levels.jpeg|400 px|right|thumb|Figure 4: T3 and T4 role in TSH concentration: Highlighting the problem when under or overactive on the metabolism. When an antibody is bound to TSHR and cannot respond to the negative feedback look the metabolism experiences a shift outside of equilibrium resulting in a wide array of side effects. [https://commons.wikimedia.org/wiki/File:1813_A_Classic_Negative_Feedback_Loop.jpg]]]
 The thyroid plays an essential role in the body's metabolism. The body's metabolism affects things like heart rate, digestion, temperature regulation, and many more things. When TSH is bound to TSHR, a signal is sent to produce T3 and T4. T4 is considered an inactive form and needs to be converted into T3 to become active. Those hormones then go impact cells in your body to increase or decrease your metabolism. The T3 and T4 hormones use a feedback system to regulate the release of TSH. When the hormone levels are high they travel through the bloodstream to prevent TSH production. When the hormones are low they are not able to continue the negative feedback loop, thus allowing TSH to be released to bind to TSHR.
 === Hyperthyroidism ===