Sandbox Reserved 1771: Difference between revisions

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===B-cell Formation===

[[Image: FINAL1.PNG| 500 px|thumb | right| '''Figure 2.''']]

[[Image: FINAL1.PNG| 500 px|thumb | right| '''Figure 2.''' Figure 2. Diagram of B-cell formation and subsequent attack of somatic cells. All cell types are labeled and BCRs are shown in red, while antigens are shown in blue. When a defective BCR recognizes a somatic cell instead of a foreign pathogen, an immune response occurs, leading to autoimmune disorders.]]

The formation of B-cells occurs in the bone marrow from hematopoietic stem cells<ref name="Althwaiqeb">Althwaiqeb, S. ''Histology, B Cell Lymphocyte''; StatPearls Publishing, 2023. </ref>. Once formed, B-cell receptors are attached to B-cells through the aid of membrane-bound proteins in bone marrow cells. During this process, gene recombination occurs, which allows unique BCRs to become highly specific to different antigens. Once they are formed, [https://en.wikipedia.org/wiki/B_cell B-cells diverge] and become either memory cells or plasma cells. Memory cells still have BCRs and initiate a faster immune response, while plasma cells secrete antibodies in response to foreign antigens.

Sandbox Reserved 1771: Difference between revisions

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@@ Line 26: / Line 26: @@
 ===B-cell Formation===
-[[Image: FINAL1.PNG| 500 px|thumb | right| '''Figure 2.''']]
+[[Image: FINAL1.PNG| 500 px|thumb | right| '''Figure 2.''' Figure 2. Diagram of B-cell formation and subsequent attack of somatic cells. All cell types are labeled and BCRs are shown in red, while antigens are shown in blue. When a defective BCR recognizes a somatic cell instead of a foreign pathogen, an immune response occurs, leading to autoimmune disorders.]]
 The formation of B-cells occurs in the bone marrow from hematopoietic stem cells<ref name="Althwaiqeb">Althwaiqeb, S. ''Histology, B Cell Lymphocyte''; StatPearls Publishing, 2023. </ref>. Once formed, B-cell receptors are attached to B-cells through the aid of membrane-bound proteins in bone marrow cells. During this process, gene recombination occurs, which allows unique BCRs to become highly specific to different antigens. Once they are formed, [https://en.wikipedia.org/wiki/B_cell B-cells diverge] and become either memory cells or plasma cells. Memory cells still have BCRs and initiate a faster immune response, while plasma cells secrete antibodies in response to foreign antigens.