Sandbox Reserved 1777: Difference between revisions

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==SHOC2==

SHOC2 is a scaffolding protein which acts as a cradle to bind PP1C and MRAS <ref name="Hauseman" />, serving as an aggregation point to enable reciprocal interactions between these three signaling proteins. <scene name='95/952705/Shoc2_structure/2'>SHOC2</scene> is a leucine rich repeat ([https://en.wikipedia.org/wiki/Leucine-rich_repeat LRR]) protein consisting of 20 consecutive <scene name='95/952706/Shoc2_structure/9'>LRR motifs</scene> containing <scene name='95/952705/Shoc2_structure/3'>leucine residues</scene>. LRR motifs form an extended β-sheet on the inner concave surface of SHOC2 with α-helices facing outward to facilitate binding of the protein complex. These LRR motifs result in a largely hydrophobic core within the concave region <ref name="Hahn" />.

SHOC2 is a scaffolding protein which acts as a cradle to bind PP1C and MRAS <ref name="Hauseman" />, serving as an aggregation point to enable reciprocal interactions between these three signaling proteins. <scene name='95/952705/Shoc2_structure/2'>SHOC2</scene> is a leucine rich repeat ([https://en.wikipedia.org/wiki/Leucine-rich_repeat LRR]) protein consisting of 20 consecutive <scene name='95/952706/Shoc2_structure/9'>LRR motifs</scene> containing <scene name='95/952705/Shoc2_structure/3'>leucine residues</scene>. LRR motifs form an extended β-sheet on the inner concave surface of SHOC2 with α-helices facing outward to facilitate binding of the protein complex. These LRR motifs result in a largely hydrophobic core within the concave region<ref name="Hahn" />.

==PP1C==

Sandbox Reserved 1777: Difference between revisions

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@@ Line 16: / Line 16: @@
 ==SHOC2==
-SHOC2 is a scaffolding protein which acts as a cradle to bind PP1C and MRAS <ref name="Hauseman" />, serving as an aggregation point to enable reciprocal interactions between these three signaling proteins. <scene name='95/952705/Shoc2_structure/2'>SHOC2</scene> is a leucine rich repeat ([https://en.wikipedia.org/wiki/Leucine-rich_repeat LRR]) protein consisting of 20 consecutive <scene name='95/952706/Shoc2_structure/9'>LRR motifs</scene> containing <scene name='95/952705/Shoc2_structure/3'>leucine residues</scene>. LRR motifs form an extended β-sheet on the inner concave surface of SHOC2 with α-helices facing outward to facilitate binding of the protein complex. These LRR motifs result in a largely hydrophobic core within the concave region <ref name="Hahn" />.
+SHOC2 is a scaffolding protein which acts as a cradle to bind PP1C and MRAS <ref name="Hauseman" />, serving as an aggregation point to enable reciprocal interactions between these three signaling proteins. <scene name='95/952705/Shoc2_structure/2'>SHOC2</scene> is a leucine rich repeat ([https://en.wikipedia.org/wiki/Leucine-rich_repeat LRR]) protein consisting of 20 consecutive <scene name='95/952706/Shoc2_structure/9'>LRR motifs</scene> containing <scene name='95/952705/Shoc2_structure/3'>leucine residues</scene>. LRR motifs form an extended β-sheet on the inner concave surface of SHOC2 with α-helices facing outward to facilitate binding of the protein complex. These LRR motifs result in a largely hydrophobic core within the concave region<ref name="Hahn" />.
 ==PP1C==