Sandbox Reserved 1791: Difference between revisions
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=== Hypothyroidism === | === Hypothyroidism === | ||
[https://www.mayoclinic.org/diseases-conditions/hypothyroidism/symptoms-causes/syc-20350284#:~:text=Hypothyroidism%20happens%20when%20the%20thyroid,symptoms%20in%20its%20early%20stages Hypothyroidism] is when the thyroid is underactive. The underactive state is initiated when antibodies like K1 are bound. When the K1 antibody is bound it does not allow the TSHR to go into the upright, active, position. This does not allow for the signaling of the T3 and T4 hormones to upregulate the metabolism. When stuck in the inactive form, TSH or M22 cannot bind to the TSHR to make more thyroid hormones which leads to an under-stimulation of the metabolism. The symptoms of this include slow or irregular heartbeats, tiredness, muscle aches, memory problems, jaundice, and sensitivity to cold. [https://www.mayoclinic.org/diseases-conditions/hashimotos-disease/symptoms-causes/syc-20351855 Hasimoto's disease] is an example of hypothyroidism. This is an autoimmune disorder that causes your body to attack the healthy cells of the thyroid. Specifically causing the death of the cells that produce the thyroid hormones. When the thyroid fails to produce its hormones it activates TSH production through a negative feedback mechanism<ref name="Luca">. | [https://www.mayoclinic.org/diseases-conditions/hypothyroidism/symptoms-causes/syc-20350284#:~:text=Hypothyroidism%20happens%20when%20the%20thyroid,symptoms%20in%20its%20early%20stages Hypothyroidism] is when the thyroid is underactive. The underactive state is initiated when antibodies like K1 are bound. When the K1 antibody is bound it does not allow the TSHR to go into the upright, active, position. This does not allow for the signaling of the T3 and T4 hormones to upregulate the metabolism. When stuck in the inactive form, TSH or M22 cannot bind to the TSHR to make more thyroid hormones which leads to an under-stimulation of the metabolism. The symptoms of this include slow or irregular heartbeats, tiredness, muscle aches, memory problems, jaundice, and sensitivity to cold. [https://www.mayoclinic.org/diseases-conditions/hashimotos-disease/symptoms-causes/syc-20351855 Hasimoto's disease] is an example of hypothyroidism. This is an autoimmune disorder that causes your body to attack the healthy cells of the thyroid. Specifically causing the death of the cells that produce the thyroid hormones. When the thyroid fails to produce its hormones it activates TSH production through a negative feedback mechanism<ref name="Luca">. | ||
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== Student Contributions == | == Student Contributions == | ||
*Alex Kem | *Alex Kem | ||
