8of4: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Nucleosome Bound human SIRT6 (Composite)== | |||
<StructureSection load='8of4' size='340' side='right'caption='[[8of4]], [[Resolution|resolution]] 2.94Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8of4]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OF4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OF4 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.94Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8of4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8of4 OCA], [https://pdbe.org/8of4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8of4 RCSB], [https://www.ebi.ac.uk/pdbsum/8of4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8of4 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Ben-Shem | == Function == | ||
[[Category: Papai | [https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
[[Category: Schultz | __TOC__ | ||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Xenopus laevis]] | |||
[[Category: Ben-Shem A]] | |||
[[Category: Bignon E]] | |||
[[Category: Papai G]] | |||
[[Category: Schultz P]] | |||
[[Category: Smirnova E]] | |||
Latest revision as of 05:31, 9 August 2023
Nucleosome Bound human SIRT6 (Composite)
| ||||||||||||
