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'''Unreleased structure'''


The entry 8j78 is ON HOLD
==Human 3-methylcrotonyl-CoA carboxylase in BCCP-H2 state==
 
<StructureSection load='8j78' size='340' side='right'caption='[[8j78]], [[Resolution|resolution]] 3.88&Aring;' scene=''>
Authors: Liu, D.S., Su, J.Y.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8j78]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8J78 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8J78 FirstGlance]. <br>
Description: Human 3-methylcrotonyl-CoA carboxylase in BCCP-H2 state
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.88&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTI:5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL'>BTI</scene></td></tr>
[[Category: Liu, D.S]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8j78 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8j78 OCA], [https://pdbe.org/8j78 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8j78 RCSB], [https://www.ebi.ac.uk/pdbsum/8j78 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8j78 ProSAT]</span></td></tr>
[[Category: Su, J.Y]]
</table>
== Disease ==
[https://www.uniprot.org/uniprot/MCCB_HUMAN MCCB_HUMAN] 3-methylcrotonyl-CoA carboxylase deficiency. The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/MCCB_HUMAN MCCB_HUMAN] Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.<ref>PMID:17360195</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Liu DS]]
[[Category: Su JY]]
Retrieved from "https://proteopedia.org/8j78"