8ok2: Difference between revisions
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==Bipartite interaction of TOPBP1 with the GINS complex== | |||
<StructureSection load='8ok2' size='340' side='right'caption='[[8ok2]], [[Resolution|resolution]] 4.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8ok2]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OK2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OK2 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.1Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ok2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ok2 OCA], [https://pdbe.org/8ok2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ok2 RCSB], [https://www.ebi.ac.uk/pdbsum/8ok2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ok2 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PSF1_HUMAN PSF1_HUMAN] The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. GINS1 is essential for function.<ref>PMID:17417653</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Day M]] | |||
[[Category: Oliver AW]] | |||
[[Category: Pearl LH]] | |||