8ow4: Difference between revisions
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==2.75 angstrom crystal structure of human NFAT1 with bound DNA== | |||
<StructureSection load='8ow4' size='340' side='right'caption='[[8ow4]], [[Resolution|resolution]] 2.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8ow4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OW4 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ow4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ow4 OCA], [https://pdbe.org/8ow4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ow4 RCSB], [https://www.ebi.ac.uk/pdbsum/8ow4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ow4 ProSAT]</span></td></tr> | ||
[[Category: Erausquin | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/NFAC2_HUMAN NFAC2_HUMAN] Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.<ref>PMID:21871017</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Erausquin E]] | |||
[[Category: Hernandez-Morales S]] | |||
[[Category: Lasarte JJ]] | |||
[[Category: Lopez-Sagaseta J]] | |||
[[Category: Lozano T]] | |||
[[Category: Urdiciain A]] | |||
Latest revision as of 12:41, 26 July 2023
2.75 angstrom crystal structure of human NFAT1 with bound DNA
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