7qri

Regulatory domain dimer of tryptophan hydroxylase 2 in complex with L-Phe

spinqualitylabelsall models 7qri Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7qri is a 2 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: PHE Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease TPH2_HUMAN Disease susceptibility is associated with variations affecting the gene represented in this entry. Disease susceptibility is associated with variations affecting the gene represented in this entry. Naturally occurring variants of TPH2 with impaired enzyme activity could cause deficiency of serotonin production and result in an increased risk of developing behavioral disorders. Function TPH2_HUMAN See Also Hydroxylases 3D structures

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