8siy: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8siy is ~~ON HOLD until Paper Publication~~

==Origin Recognition Complex Associated (ORCA) protein bound to H4K20me3-nucleosome==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8siy]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SIY OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=8SIY FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ML3:2-{[(2R)-2-AMINO-2-CARBOXYETHYL]SULFANYL}-N,N,N-TRIMETHYLETHANAMINIUM'>ML3</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=8siy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8siy OCA], [https://pdbe.org/8siy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8siy RCSB], [https://www.ebi.ac.uk/pdbsum/8siy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8siy ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/H2B11_XENLA H2B11_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Rattus norvegicus]]

[[Category: Synthetic construct]]

[[Category: Xenopus laevis]]

[[Category: Bleichert F]]

[[Category: Ekundayo BE]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8siy is ON HOLD  until Paper Publication
+==Origin Recognition Complex Associated (ORCA) protein bound to H4K20me3-nucleosome==
+<StructureSection load='8siy' size='340' side='right'caption='[[8siy]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8siy]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SIY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SIY FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ML3:2-{[(2R)-2-AMINO-2-CARBOXYETHYL]SULFANYL}-N,N,N-TRIMETHYLETHANAMINIUM'>ML3</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8siy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8siy OCA], [https://pdbe.org/8siy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8siy RCSB], [https://www.ebi.ac.uk/pdbsum/8siy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8siy ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/H2B11_XENLA H2B11_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Rattus norvegicus]]
+[[Category: Synthetic construct]]
+[[Category: Xenopus laevis]]
+[[Category: Bleichert F]]
+[[Category: Ekundayo BE]]