8oq6: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8oq6 is ~~ON HOLD until Paper Publication~~

==CryoEM structure of human rho1 GABAA receptor apo state==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8oq6]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OQ6 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=8OQ6 FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.21Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7P9:[(2R)-2-HEPTANOYLOXY-3-PHOSPHONOOXY-PROPYL]+NONANOATE'>7P9</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=D10:DECANE'>D10</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OCT:N-OCTANE'>OCT</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=8oq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8oq6 OCA], [https://pdbe.org/8oq6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8oq6 RCSB], [https://www.ebi.ac.uk/pdbsum/8oq6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8oq6 ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/GBRR1_HUMAN GBRR1_HUMAN] GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Chen F]]

[[Category: Erik L]]

[[Category: John C]]

[[Category: Rebecca JH]]

[[Category: Victor T]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8oq6 is ON HOLD  until Paper Publication
+==CryoEM structure of human rho1 GABAA receptor apo state==
+<StructureSection load='8oq6' size='340' side='right'caption='[[8oq6]], [[Resolution|resolution]] 3.21&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8oq6]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OQ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OQ6 FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.21&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7P9:[(2R)-2-HEPTANOYLOXY-3-PHOSPHONOOXY-PROPYL]+NONANOATE'>7P9</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=D10:DECANE'>D10</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OCT:N-OCTANE'>OCT</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8oq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8oq6 OCA], [https://pdbe.org/8oq6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8oq6 RCSB], [https://www.ebi.ac.uk/pdbsum/8oq6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8oq6 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/GBRR1_HUMAN GBRR1_HUMAN] GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Chen F]]
+[[Category: Erik L]]
+[[Category: John C]]
+[[Category: Rebecca JH]]
+[[Category: Victor T]]