8sl1: Difference between revisions

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'''Unreleased structure'''


The entry 8sl1 is ON HOLD  until Paper Publication
==Cryo-EM structure of PAPP-A2==
 
<StructureSection load='8sl1' size='340' side='right'caption='[[8sl1]], [[Resolution|resolution]] 3.13&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8sl1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SL1 FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.13&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sl1 OCA], [https://pdbe.org/8sl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sl1 RCSB], [https://www.ebi.ac.uk/pdbsum/8sl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sl1 ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/PAPP2_HUMAN PAPP2_HUMAN] The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/PAPP2_HUMAN PAPP2_HUMAN] Metalloproteinase which specifically cleaves insulin-like growth factor binding protein (IGFBP)-5 at the '163-Ser-|-Lys-164' bond. Shows limited proteolysis toward IGFBP-3.<ref>PMID:11264294</ref> <ref>PMID:26902202</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bratkowski MA]]
[[Category: Eaton D]]
[[Category: Hao Q]]
[[Category: Judge RA]]
[[Category: Stoll VS]]
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