1l3a: Difference between revisions

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[[Image:1l3a.~~jpg~~|left|200px]]

[[Image:1l3a.png|left|200px]]

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~~'''~~Structure of the plant transcriptional regulator PBF-2~~'''~~

===Structure of the plant transcriptional regulator PBF-2===

~~==Overview==~~

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The ~~crystal structure of p24~~, the ~~single-stranded DNA~~ (ssDNA) binding subunit of the plant defense transcription factor PBF-2, has been determined to 2.3 A resolution. p24 is representative of a novel family of ubiquitous plant-specific proteins that we refer to as ~~the Whirly family because of their quaternary structure. PBF-2 is composed of four p24 molecules that interact through a helix-loop-helix motif~~. ~~This interaction produces a central pore, with beta-strands radiating outwards, resulting in a whirligig appearance to the quaternary structure~~. ~~The noncrystallographic C(4~~) ~~symmetry arrangement of p24 subunits~~ is ~~novel for ssDNA binding proteins and may explain~~ the ~~binding specificity of PBF~~-~~2. This structural arrangement also supports the role of PBF~~-~~2 in binding melted promoter regions to modulate gene expression.~~

The line below this paragraph, {{ABSTRACT_PUBMED_12080340}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 12080340 is the PubMed ID number.

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==About this Structure==

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[[Category: Transcriptionnal activator]]

[[Category: Whirly]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri May~~ 2 23:29:31 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 11:36:25 2008''

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-[[Image:1l3a.jpg|left|200px]]
+{{Seed}}
+[[Image:1l3a.png|left|200px]]
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 {{STRUCTURE_1l3a|  PDB=1l3a  |  SCENE=  }}
-'''Structure of the plant transcriptional regulator PBF-2'''
+===Structure of the plant transcriptional regulator PBF-2===
-==Overview==
+<!--
-The crystal structure of p24, the single-stranded DNA (ssDNA) binding subunit of the plant defense transcription factor PBF-2, has been determined to 2.3 A resolution. p24 is representative of a novel family of ubiquitous plant-specific proteins that we refer to as the Whirly family because of their quaternary structure. PBF-2 is composed of four p24 molecules that interact through a helix-loop-helix motif. This interaction produces a central pore, with beta-strands radiating outwards, resulting in a whirligig appearance to the quaternary structure. The noncrystallographic C(4) symmetry arrangement of p24 subunits is novel for ssDNA binding proteins and may explain the binding specificity of PBF-2. This structural arrangement also supports the role of PBF-2 in binding melted promoter regions to modulate gene expression.
+The line below this paragraph, {{ABSTRACT_PUBMED_12080340}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 12080340 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_12080340}}
 ==About this Structure==
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 [[Category: Transcriptionnal activator]]
 [[Category: Whirly]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 23:29:31 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 11:36:25 2008''