8jpe: Difference between revisions

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'''Unreleased structure'''


The entry 8jpe is ON HOLD  until Paper Publication
==Focused refinement structure of Galpha(q) in NTSR1-GRK2-Galpha(q) complexes==
 
<StructureSection load='8jpe' size='340' side='right'caption='[[8jpe]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
Authors: Duan, J., Liu, H., Zhao, F., Yuan, Q., Ji, Y., Xu, H.E.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8jpe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JPE FirstGlance]. <br>
Description: Focused refinement structure of Galpha(q) in NTSR1-GRK2-Galpha(q) complexes
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.91&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
[[Category: Xu, H.E]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jpe OCA], [https://pdbe.org/8jpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jpe RCSB], [https://www.ebi.ac.uk/pdbsum/8jpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jpe ProSAT]</span></td></tr>
[[Category: Duan, J]]
</table>
[[Category: Zhao, F]]
== Disease ==
[[Category: Liu, H]]
[https://www.uniprot.org/uniprot/GNAQ_HUMAN GNAQ_HUMAN] Sturge-Weber syndrome;Phakomatosis cesioflammea;Uveal melanoma;Familial multiple nevi flammei. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
[[Category: Yuan, Q]]
== Function ==
[[Category: Ji, Y]]
[https://www.uniprot.org/uniprot/GNAQ_HUMAN GNAQ_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity).
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Duan J]]
[[Category: Ji Y]]
[[Category: Liu H]]
[[Category: Xu HE]]
[[Category: Yuan Q]]
[[Category: Zhao F]]
Retrieved from "https://proteopedia.org/8jpe"