1lev: Difference between revisions

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[[Image:1lev.jpg|left|200px]]
{{Seed}}
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{{STRUCTURE_1lev|  PDB=1lev  |  SCENE=  }}  
{{STRUCTURE_1lev|  PDB=1lev  |  SCENE=  }}  


'''PORCINE KIDNEY FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH AN AMP-SITE INHIBITOR'''
===PORCINE KIDNEY FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH AN AMP-SITE INHIBITOR===




==Overview==
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3-(2-Carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid (MDL-29951), an antagonist of the glycine site of the NMDA receptor, has been found to be an allosteric inhibitor of the enzyme fructose 1,6-bisphosphatase. The compound binds at the AMP regulatory site by X-ray crystallography. This represents a new approach to inhibition of fructose 1,6-bisphosphatase and serves as a lead for further drug design.
The line below this paragraph, {{ABSTRACT_PUBMED_12781194}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 12781194 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12781194}}


==About this Structure==
==About this Structure==
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[[Category: Wright, S W.]]
[[Category: Wright, S W.]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 23:51:15 2008''
 
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