8ou0: Difference between revisions
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== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/TBB4B_BOVIN TBB4B_BOVIN] Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed: | [https://www.uniprot.org/uniprot/TBB4B_BOVIN TBB4B_BOVIN] Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:2207090, PubMed:6504138, PubMed:7704569). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:2207090, PubMed:6504138, PubMed:7704569).<ref>PMID:2207090</ref> <ref>PMID:6504138</ref> <ref>PMID:7704569</ref> | ||
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== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | |||
*[[Tubulin 3D Structures|Tubulin 3D Structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
