1lft: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
Line 1: Line 1:
[[Image:1lft.gif|left|200px]]
{{Seed}}
[[Image:1lft.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1lft|  PDB=1lft  |  SCENE=  }}  
{{STRUCTURE_1lft|  PDB=1lft  |  SCENE=  }}  


'''OXY HEMOGLOBIN (90% RELATIVE HUMIDITY)'''
===OXY HEMOGLOBIN (90% RELATIVE HUMIDITY)===




==Overview==
<!--  
High-salt crystals of human oxy- and deoxyhaemoglobin have been studied at different levels of environmental humidity and solvent content. The structure of the oxy form remains relatively unchanged at all levels. The deoxy form, however, undergoes a water-mediated transformation when the relative humidity around the crystals is reduced below 93%. The space group is maintained during the transformation, but the unit-cell volume nearly doubles, with two tetrameric molecules in the asymmetric unit of the low-humidity form compared with one in the native crystals. Interestingly, the haem geometry in the low-humidity form is closer to that in the oxy form than to that in the native deoxy form. The quaternary structure of one of the tetramers moves slightly towards that in the oxy form, while that in the other is more different from the oxy form than that in the high-salt native deoxy form. Thus, it would appear that, as in the case of the liganded form, the deoxy form of haemoglobin can also access an ensemble of related T states.
The line below this paragraph, {{ABSTRACT_PUBMED_12077435}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 12077435 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_12077435}}


==About this Structure==
==About this Structure==
Line 28: Line 32:
[[Category: Humidity]]
[[Category: Humidity]]
[[Category: T state]]
[[Category: T state]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 23:53:09 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 20:49:15 2008''

Revision as of 17:50, 2 July 2008

File:1lft.png

Template:STRUCTURE 1lft

OXY HEMOGLOBIN (90% RELATIVE HUMIDITY)

Template:ABSTRACT PUBMED 12077435

About this Structure

1LFT is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structures of human oxy- and deoxyhaemoglobin at different levels of humidity: variability in the T state., Biswal BK, Vijayan M, Acta Crystallogr D Biol Crystallogr. 2002 Jul;58(Pt 7):1155-61. Epub 2002, Jun 20. PMID:12077435

Page seeded by OCA on Wed Jul 2 20:49:15 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1lft&oldid=625276"