8k3d: Difference between revisions
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==Crystal structure of NRF1 DBD bound to DNA== | |||
<StructureSection load='8k3d' size='340' side='right'caption='[[8k3d]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8k3d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8K3D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8K3D FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8k3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8k3d OCA], [https://pdbe.org/8k3d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8k3d RCSB], [https://www.ebi.ac.uk/pdbsum/8k3d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8k3d ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Liu | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/NRF1_HUMAN NRF1_HUMAN] Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Li WF]] | |||
[[Category: Liu K]] | |||
[[Category: Min JR]] | |||
Latest revision as of 08:02, 6 December 2023
Crystal structure of NRF1 DBD bound to DNA
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