8k5t: Difference between revisions
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The | ==The structure of EntE with2-methyl-3-chloro-benzoic acid sulfamoyl adenosine== | ||
<StructureSection load='8k5t' size='340' side='right'caption='[[8k5t]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8k5t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8K5T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8K5T FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VQ5:[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl+~{N}-(3-chloranyl-2-methyl-phenyl)carbonylsulfamate'>VQ5</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8k5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8k5t OCA], [https://pdbe.org/8k5t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8k5t RCSB], [https://www.ebi.ac.uk/pdbsum/8k5t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8k5t ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ENTE_ECOLI ENTE_ECOLI] Activates the carboxylate group of 2,3-dihydroxy-benzoate (2,3-DHB), via ATP-dependent PPi exchange reactions, to the acyladenylate. Then, catalyzes the acylation of holo-EntB with 2,3-DHB adenylate, preparing that molecule for amide bond formation with L-serine. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | |||
[[Category: Large Structures]] | |||
[[Category: Ishikawa F]] | |||
[[Category: Miyanaga A]] | |||
Latest revision as of 06:03, 31 July 2024
The structure of EntE with2-methyl-3-chloro-benzoic acid sulfamoyl adenosine
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