8q7n: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8q7n is ~~ON HOLD~~

==cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8q7n]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Q7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Q7N FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8q7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8q7n OCA], [https://pdbe.org/8q7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8q7n RCSB], [https://www.ebi.ac.uk/pdbsum/8q7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8q7n ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/SF3A1_HUMAN SF3A1_HUMAN] Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Dybkov O]]

[[Category: Kumar V]]

[[Category: Luehrmann R]]

[[Category: Stark H]]

[[Category: Urlaub H]]

[[Category: Will CL]]

[[Category: Zhang Z]]

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-'''Unreleased structure'''
-The entry 8q7n is ON HOLD
+==cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)==
+<StructureSection load='8q7n' size='340' side='right'caption='[[8q7n]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8q7n]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Q7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Q7N FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8q7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8q7n OCA], [https://pdbe.org/8q7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8q7n RCSB], [https://www.ebi.ac.uk/pdbsum/8q7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8q7n ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SF3A1_HUMAN SF3A1_HUMAN] Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Dybkov O]]
+[[Category: Kumar V]]
+[[Category: Luehrmann R]]
+[[Category: Stark H]]
+[[Category: Urlaub H]]
+[[Category: Will CL]]
+[[Category: Zhang Z]]