1mov: Difference between revisions

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[[Image:1mov.gif|left|200px]]
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{{STRUCTURE_1mov|  PDB=1mov  |  SCENE=  }}  
{{STRUCTURE_1mov|  PDB=1mov  |  SCENE=  }}  


'''Crystal structure of Coral protein mutant'''
===Crystal structure of Coral protein mutant===




==Overview==
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Reef-building corals contain host pigments, termed pocilloporins, that function to regulate the light environment of their resident microalgae by acting as a photoprotectant in excessive sunlight. We have determined the crystal structure of an intensely blue, nonfluorescent pocilloporin to 2.2 A resolution and a genetically engineered fluorescent variant to 2.4 A resolution. The pocilloporin chromophore structure adopts a markedly different conformation in comparison with the DsRed chromophore, despite the chromophore sequences (Gln-Tyr-Gly) being identical; the tyrosine ring of the pocilloporin chromophore is noncoplanar and in the trans configuration. Furthermore, the fluorescent variant adopted a noncoplanar chromophore conformation. The data presented here demonstrates that the conformation of the chromophore is highly dependent on its immediate environment.
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{{ABSTRACT_PUBMED_12623015}}


==About this Structure==
==About this Structure==
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[[Category: Fluorescent conversion mutant]]
[[Category: Fluorescent conversion mutant]]
[[Category: Rtms5]]
[[Category: Rtms5]]
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Revision as of 21:36, 2 July 2008

File:1mov.png

Template:STRUCTURE 1mov

Crystal structure of Coral protein mutant

Template:ABSTRACT PUBMED 12623015

About this Structure

1MOV is a Single protein structure of sequence from Montipora efflorescens. Full crystallographic information is available from OCA.

Reference

The 2.2 A crystal structure of a pocilloporin pigment reveals a nonplanar chromophore conformation., Prescott M, Ling M, Beddoe T, Oakley AJ, Dove S, Hoegh-Guldberg O, Devenish RJ, Rossjohn J, Structure. 2003 Mar;11(3):275-84. PMID:12623015

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