1mwe: Difference between revisions

Line 1:

[[Image:1mwe.~~gif~~|left|200px]]

[[Image:1mwe.png|left|200px]]

<!--

Line 9:

Line 10:

~~'''~~THE X-RAY STRUCTURE OF A COMPLEX OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE COMPLEXED WITH SIALIC ACID AT 4 DEGREES C REVEALING A SECOND SIALIC ACID BINDING SITE~~'''~~

===THE X-RAY STRUCTURE OF A COMPLEX OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE COMPLEXED WITH SIALIC ACID AT 4 DEGREES C REVEALING A SECOND SIALIC ACID BINDING SITE===

~~==Overview==~~

<!--

The ~~x-ray structure of a complex of sialic acid~~ (~~Neu5Ac) with neuraminidase N9 subtype from A~~/~~tern~~/~~Australia/G70C/75 influenza virus at 4 degrees C has revealed the location of a second Neu5Ac binding site on the surface of the enzyme~~. ~~At 18 degrees C~~, ~~only~~ the ~~enzyme active site contains bound Neu5Ac~~. Neu5Ac binds in the second site in the chair conformation in a similar way to which it binds to hemagglutinin. The residues that interact with Neu5Ac at this second site are mostly conserved in avian strains, but not in human and swine strains, indicating that it has some as-~~yet~~-~~unknown biological function in birds.~~

The line below this paragraph, {{ABSTRACT_PUBMED_9342319}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 9342319 is the PubMed ID number.

-->

==About this Structure==

Line 30:

Line 34:

[[Category: Neuraminidase]]

[[Category: Sialic acid binding]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 01~~:48:04 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 22:15:11 2008''

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-[[Image:1mwe.gif|left|200px]]
+{{Seed}}
+[[Image:1mwe.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_1mwe|  PDB=1mwe  |  SCENE=  }}
-'''THE X-RAY STRUCTURE OF A COMPLEX OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE COMPLEXED WITH SIALIC ACID AT 4 DEGREES C REVEALING A SECOND SIALIC ACID BINDING SITE'''
+===THE X-RAY STRUCTURE OF A COMPLEX OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE COMPLEXED WITH SIALIC ACID AT 4 DEGREES C REVEALING A SECOND SIALIC ACID BINDING SITE===
-==Overview==
+<!--
-The x-ray structure of a complex of sialic acid (Neu5Ac) with neuraminidase N9 subtype from A/tern/Australia/G70C/75 influenza virus at 4 degrees C has revealed the location of a second Neu5Ac binding site on the surface of the enzyme. At 18 degrees C, only the enzyme active site contains bound Neu5Ac. Neu5Ac binds in the second site in the chair conformation in a similar way to which it binds to hemagglutinin. The residues that interact with Neu5Ac at this second site are mostly conserved in avian strains, but not in human and swine strains, indicating that it has some as-yet-unknown biological function in birds.
+The line below this paragraph, {{ABSTRACT_PUBMED_9342319}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 9342319 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_9342319}}
 ==About this Structure==
@@ Line 30: / Line 34: @@
 [[Category: Neuraminidase]]
 [[Category: Sialic acid binding]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 01:48:04 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 22:15:11 2008''